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Hector G Ortega Selected Research

mepolizumab

9/2019Update on immunogenicity in severe asthma: Experience with mepolizumab.
1/2019Efficacy of add-on mepolizumab in adolescents with severe eosinophilic asthma.
1/2019Association of depressive symptoms with health status and markers of uncontrolled severe asthma.
4/2017Meta-analysis of asthma-related hospitalization in mepolizumab studies of severe eosinophilic asthma.
9/2016Long-term Efficacy and Safety of Mepolizumab in Patients With Severe Eosinophilic Asthma: A Multi-center, Open-label, Phase IIIb Study.
1/2016Severe eosinophilic asthma treated with mepolizumab stratified by baseline eosinophil thresholds: a secondary analysis of the DREAM and MENSA studies.
12/2015Characterization of the relationship between dose and blood eosinophil response following subcutaneous administration of mepolizumab.
12/2014Glucocorticoids and mepolizumab in eosinophilic asthma.
9/2014Oral glucocorticoid-sparing effect of mepolizumab in eosinophilic asthma.
9/2014Mepolizumab treatment in patients with severe eosinophilic asthma.
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Hector G Ortega Research Topics

Disease

22Asthma (Bronchial Asthma)
09/2019 - 12/2007
3Inflammation (Inflammations)
01/2016 - 11/2011
2Overweight
02/2010 - 01/2010
1Anaphylaxis (Anaphylactic Shock)
09/2016
1Hypereosinophilic Syndrome (Loeffler Endocarditis)
02/2013
1Eosinophilia
02/2013
1Eosinophilic Esophagitis
11/2011
1Allergic Rhinitis
01/2010
1Seasonal Allergic Rhinitis (Hay Fever)
01/2010
1Rhinitis
01/2010
1Exercise-Induced Asthma (Asthma, Exercise Induced)
05/2009
1Tremor (Tremors)
02/2009
1Deglutition Disorders (Dysphagia)
02/2009
1Dysphonia (Spastic Dysphonia)
02/2009
1Bronchitis
02/2009
1Extrinsic Allergic Alveolitis (Hypersensitivity Pneumonitis)
04/2005

Drug/Important Bio-Agent (IBA)

13mepolizumabIBA
09/2019 - 11/2011
5Adrenal Cortex Hormones (Corticosteroids)IBA
09/2016 - 04/2008
5Fluticasone-Salmeterol Drug Combination (Advair)FDA Link
04/2010 - 04/2009
5Fluticasone (Cutivate)FDA LinkGeneric
04/2010 - 02/2009
4Salmeterol Xinafoate (Serevent)FDA Link
04/2010 - 02/2009
3GlucocorticoidsIBA
12/2014 - 09/2014
3montelukast (Singulair)FDA Link
02/2010 - 01/2010
3Albuterol (Salbutamol)FDA LinkGeneric
02/2010 - 01/2010
2Biomarkers (Surrogate Marker)IBA
01/2016 - 05/2014
2Interleukin-5 (Interleukin 5)IBA
09/2014 - 11/2011
1Monoclonal AntibodiesIBA
09/2014
1InterleukinsIBA
11/2011
1SteroidsIBA
04/2010
1Arginine (L-Arginine)FDA Link
04/2010
13- (2- (4- azidobenzamidino)ethyl)- 5- hydroxyindole (SABA)IBA
04/2010
1Nasal SpraysIBA
01/2010
1AerosolsIBA
04/2009
1apaflurane (hydrofluoroalkane)IBA
04/2009
1PowdersIBA
02/2009
1Pharmaceutical PreparationsIBA
02/2009
1Bronchodilator Agents (Bronchodilators)IBA
12/2007
1AntigensIBA
04/2005

Therapy/Procedure

8Therapeutics
09/2016 - 01/2010
1Polypharmacy
01/2019
1Aftercare (After-Treatment)
04/2009
1Metered Dose Inhalers (Metered Dose Inhaler)
04/2009
1Dry Powder Inhalers
02/2009
1Nebulizers and Vaporizers (Inhaler)
02/2009